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Chronic E-Cigarette Use Increases Neutrophil Elastase and Matrix Metalloprotease Levels in the Lung
Rationale: Proteolysis is a key aspect of the lung’s innate immune system. Proteases, including neutrophil elastase and MMPs (matrix metalloproteases), modulate cell signaling, inflammation, tissue remodeling, and leukocyte recruitment via cleavage of their target proteins. Excessive proteolysis occ...
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| Vydáno v: | Am J Respir Crit Care Med |
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| Hlavní autoři: | , , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
American Thoracic Society
2019
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6884043/ https://ncbi.nlm.nih.gov/pubmed/31390877 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1164/rccm.201903-0615OC |
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