Neutrophil Elastase Contributes to Cigarette Smoke-Induced Emphysema in Mice

To address the role of neutrophil elastase in pulmonary emphysema, neutrophil elastase-deficient mice and wild-type littermate controls were exposed to long-term cigarette smoke. Compared to wild-type littermates, mice that were deficient in neutrophil elastase were significantly protected (59%) fro...

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Hlavní autoři: Shapiro, Steven D., Goldstein, Nir M., Houghton, A. McGarry, Kobayashi, Dale K., Kelley, Diane, Belaaouaj, Abderazzaq
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Investigative Pathology 2003
Témata:
Regular Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1892384/
https://ncbi.nlm.nih.gov/pubmed/14633606
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