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Superoxide Dismutase Expression Attenuates Cigarette Smoke– or Elastase-generated Emphysema in Mice

RATIONALE: Oxidants are believed to play a major role in the development of emphysema. OBJECTIVES: This study aimed to determine if the expression of human copper–zinc superoxide dismutase (CuZnSOD) within the lungs of mice protects against the development of emphysema. METHODS: Transgenic CuZnSOD a...

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Detalhes bibliográficos
Main Authors: Foronjy, Robert F., Mirochnitchenko, Oleg, Propokenko, Olga, Lemaitre, Vincent, Jia, Yuxia, Inouye, Masayori, Okada, Yasunori, D’Armiento, Jeanine M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3982860/
https://ncbi.nlm.nih.gov/pubmed/16387805
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1164/rccm.200506-850OC
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