Extracellular superoxide dismutase protects against pulmonary emphysema by attenuating oxidative fragmentation of ECM

Extracellular superoxide dismutase (ECSOD or SOD3) is highly expressed in lungs and functions as a scavenger of O(2)(• ─). ECM fragmentation, which can be triggered by oxidative stress, participates in the pathogenesis of chronic obstructive pulmonary disease (COPD) through attracting inflammatory c...

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Tallennettuna:
Bibliografiset tiedot
Päätekijät: Yao, Hongwei, Arunachalam, Gnanapragasam, Hwang, Jae-woong, Chung, Sangwoon, Sundar, Isaac K., Kinnula, Vuokko L., Crapo, James D., Rahman, Irfan
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: National Academy of Sciences 2010
Aiheet:
Biological Sciences
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2932580/
https://ncbi.nlm.nih.gov/pubmed/20713693
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1007625107
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