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Extracellular superoxide dismutase protects against pulmonary emphysema by attenuating oxidative fragmentation of ECM
Extracellular superoxide dismutase (ECSOD or SOD3) is highly expressed in lungs and functions as a scavenger of O(2)(• ─). ECM fragmentation, which can be triggered by oxidative stress, participates in the pathogenesis of chronic obstructive pulmonary disease (COPD) through attracting inflammatory c...
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| Autori principali: | , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
National Academy of Sciences
2010
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2932580/ https://ncbi.nlm.nih.gov/pubmed/20713693 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1007625107 |
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