A murine model of elastase- and cigarette smoke-induced emphysema

OBJECTIVE: To describe a murine model of emphysema induced by a combination of exposure to cigarette smoke (CS) and instillation of porcine pancreatic elastase (PPE). METHODS: A total of 38 C57BL/6 mice were randomly divided into four groups: control (one intranasal instillation of 0.9% saline solut...

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Veröffentlicht in:J Bras Pneumol
Hauptverfasser: Rodrigues, Rubia, Olivo, Clarice Rosa, Lourenço, Juliana Dias, Riane, Alyne, Cervilha, Daniela Aparecida de Brito, Ito, Juliana Tiyaki, Martins, Milton de Arruda, Lopes, Fernanda Degobbi Tenório Quirino dos Santos
Format: Artigo
Sprache:Inglês
Veröffentlicht: Sociedade Brasileira de Pneumologia e Tisiologia 2017
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Original Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5474371/
https://ncbi.nlm.nih.gov/pubmed/28538775
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1590/S1806-37562016000000179
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