Karyopherin α2-dependent import of E2F1 and TFDP1 maintains protumorigenic stathmin expression in liver cancer

BACKGROUND: Members of the karyopherin superfamily serve as nuclear transport receptors/adaptor proteins and provide exchange of macromolecules between the nucleo- and cytoplasm. Emerging evidence suggests a subset of karyopherins to be dysregulated in hepatocarcinogenesis including karyopherin-α2 (...

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Vydáno v:Cell Commun Signal
Hlavní autoři: Drucker, Elisabeth, Holzer, Kerstin, Pusch, Stefan, Winkler, Juliane, Calvisi, Diego F., Eiteneuer, Eva, Herpel, Esther, Goeppert, Benjamin, Roessler, Stephanie, Ori, Alessandro, Schirmacher, Peter, Breuhahn, Kai, Singer, Stephan
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2019
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6883611/
https://ncbi.nlm.nih.gov/pubmed/31783876
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12964-019-0456-x
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