Inflammation-induced upregulation of P2X(4) expression augments mucin secretion in airway epithelia

Mucus clearance provides an essential innate defense mechanism to keep the airways and lungs free of particles and pathogens. Baseline and stimulated mucin secretion from secretory airway epithelial cells need to be tightly regulated to prevent mucus hypersecretion and mucus plugging of the airways....

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Detalhes bibliográficos
Publicado no:Am J Physiol Lung Cell Mol Physiol
Main Authors: Winkelmann, Veronika E., Thompson, Kristin E., Neuland, Kathrin, Jaramillo, Ana M., Fois, Giorgio, Schmidt, Hanna, Wittekindt, Oliver H., Han, Wei, Tuvim, Michael J., Dickey, Burton F., Dietl, Paul, Frick, Manfred
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6883286/
https://ncbi.nlm.nih.gov/pubmed/30358443
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00157.2018
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