MAPKAPK2 (MK2) inhibition mediates radiation-induced inflammatory cytokine production and tumor growth in head and neck squamous cell carcinoma

Radiation therapy (RT) is a cornerstone of treatment in the management of head and neck squamous cell carcinomas (HNSCC), yet treatment failure and disease recurrence are common. The p38/MK2 pathway is activated in response to cellular stressors, including radiation, and promotes tumor inflammation...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Oncogene
Main Authors: Berggren, Kiersten L., Cruz, Sebastian Restrepo, Hixon, Michael D, Cowan, Andrew, Keysar, Stephen B., Craig, Stephanie, James, Jacqueline, Barry, Marc, Ozbun, Michelle A., Jimeno, Antonio, McCance, Dennis J., Beswick, Ellen J., Gan, Gregory N.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6883149/
https://ncbi.nlm.nih.gov/pubmed/31417185
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41388-019-0945-9
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados