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Computational screening of nanoparticles coupling to Aβ40 peptides and fibrils

Blocking the formation, growth, and breaking of amyloid fibrils by synthetic nanosystems could provide a treatment of neurodegenerative diseases. With this in mind, here atomistic molecular dynamics simulations are used to screen for nanoparticles (NPs), covered with different mixtures of ligands, i...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Sen, Soumyo, Vuković, Lela, Král, Petr
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6883061/
https://ncbi.nlm.nih.gov/pubmed/31780663
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-52594-8
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