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Structural basis for virulence regulation in Vibrio cholerae by unsaturated fatty acid components of bile
The AraC/XylS-family transcriptional regulator ToxT is the master virulence activator of Vibrio cholerae, the gram-negative bacterial pathogen that causes the diarrheal disease cholera. Unsaturated fatty acids (UFAs) found in bile inhibit the activity of ToxT. Crystal structures of inhibited ToxT bo...
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| Yayımlandı: | Commun Biol |
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| Asıl Yazarlar: | , , , , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
Nature Publishing Group UK
2019
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6882843/ https://ncbi.nlm.nih.gov/pubmed/31815195 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s42003-019-0686-x |
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