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Mechanism for Inhibition of Vibrio cholerae ToxT Activity by the Unsaturated Fatty Acid Components of Bile

The Gram-negative curved bacillus Vibrio cholerae causes the severe diarrheal illness cholera. During host infection, a complex regulatory cascade results in production of ToxT, a DNA-binding protein that activates the transcription of major virulence genes that encode cholera toxin (CT) and toxin-c...

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Detalhes bibliográficos
Publicado no:J Bacteriol
Main Authors: Plecha, Sarah C., Withey, Jeffrey H.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4402388/
https://ncbi.nlm.nih.gov/pubmed/25733618
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.02409-14
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