Phenylacetyl Coenzyme A, Not Phenylacetic Acid, Attenuates CepIR-Regulated Virulence in Burkholderia cenocepacia

During phenylalanine catabolism, phenylacetic acid (PAA) is converted to phenylacetyl coenzyme A (PAA-CoA) by a ligase, PaaK, and then PAA-CoA is epoxidized by a multicomponent monooxygenase, PaaABCDE, before further degradation through the tricarboxylic acid (TCA) cycle. In the opportunistic pathog...

Полное описание

Сохранить в:
Библиографические подробности
Опубликовано в: :Appl Environ Microbiol
Главные авторы: Lightly, Tasia Joy, Frejuk, Kara L., Groleau, Marie-Christine, Chiarelli, Laurent R., Ras, Cor, Buroni, Silvia, Déziel, Eric, Sorensen, John L., Cardona, Silvia T.
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Microbiology 2019
Предметы:
Genetics and Molecular Biology
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6881814/
https://ncbi.nlm.nih.gov/pubmed/31585996
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.01594-19
Метки: Добавить метку
Нет меток, Требуется 1-ая метка записи!

Схожие документы