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Glycerol not lactate is the major net carbon source for gluconeogenesis in mice during both short and prolonged fasting

OBJECTIVE: Fasting results in major metabolic changes including a switch from glycogenolysis to gluconeogenesis to maintain glucose homeostasis. However, the relationship between the length of fasting and the relative contribution of gluconeogenic substrates remains unclear. We investigated the rela...

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Vydáno v:Mol Metab
Hlavní autoři: Wang, Yujue, Kwon, Hyokjoon, Su, Xiaoyang, Wondisford, Fredric E.
Médium: Artigo
Jazyk:Inglês
Vydáno: Elsevier 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6881678/
https://ncbi.nlm.nih.gov/pubmed/31918920
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmet.2019.11.005
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