Glycerol induces G6pc in primary mouse hepatocytes and is the preferred substrate for gluconeogenesis both in vitro and in vivo

Gluconeogenesis (GNG) is de novo production of glucose from endogenous carbon sources. Although it is a commonly studied pathway, particularly in disease, there is a lack of consensus about substrate preference. Moreover, primary hepatocytes are the current gold standard for in vitro liver studies,...

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Foilsithe in:J Biol Chem
Main Authors: Kalemba, Katarzyna M., Wang, Yujue, Xu, Huiting, Chiles, Eric, McMillin, Sara M., Kwon, Hyokjoon, Su, Xiaoyang, Wondisford, Fredric E.
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society for Biochemistry and Molecular Biology 2019
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Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6885632/
https://ncbi.nlm.nih.gov/pubmed/31645433
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.011033
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