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Cardiolipin is an Optimal Phospholipid for the Assembly, Stability, and Proper Functionality of the Dimeric Form of NhaA Na(+)/H(+) Antiporter

Cardiolipin (CL) was shown to bound to the dimer interface of NhaA Na(+)/H(+) antiporter. Here, we explore the cardiolipin-NhaA interaction both in vitro and in vivo. Using a novel and straightforward in-vitro assay in which n-dodecyl β-D maltoside (DDM) detergent is used to delipidate the dimer int...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Rimon, Abraham, Mondal, Ramakanta, Friedler, Assaf, Padan, Etana
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6881326/
https://ncbi.nlm.nih.gov/pubmed/31776461
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-54198-8
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