A cell-free biosynthesis platform for modular construction of protein glycosylation pathways

Glycosylation plays important roles in cellular function and endows protein therapeutics with beneficial properties. However, constructing biosynthetic pathways to study and engineer precise glycan structures on proteins remains a bottleneck. Here, we report a modular, versatile cell-free platform f...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Kightlinger, Weston, Duncker, Katherine E., Ramesh, Ashvita, Thames, Ariel H., Natarajan, Aravind, Stark, Jessica C., Yang, Allen, Lin, Liang, Mrksich, Milan, DeLisa, Matthew P., Jewett, Michael C.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6881289/
https://ncbi.nlm.nih.gov/pubmed/31776339
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-12024-9
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