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Splicing the innate immune signalling in leukaemia
Components of the spliceosome are frequently mutated in haematopoietic malignancies. Identification of mis-spliced genes promoting transformation will uncover novel targeted therapies. Now, a long isoform of IRAK4 is shown to be upregulated in a subset of acute myeloid leukaemia patients, conferring...
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| Publicado en: | Nat Cell Biol |
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| Autores principales: | , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2019
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6880928/ https://ncbi.nlm.nih.gov/pubmed/31011166 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41556-019-0323-4 |
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