Ether lipid metabolism by AADACL1 regulates platelet function and thrombosis

We previously reported the discovery of a novel lipid deacetylase in platelets, arylacetamide deacetylase-like 1 (AADACL1/NCEH1), and that its inhibition impairs agonist-induced platelet aggregation, Rap1 GTP loading, protein kinase C (PKC) activation, and ex vivo thrombus growth. However, precise m...

Descripció completa

Guardat en:
Dades bibliogràfiques
Publicat a:Blood Adv
Autors principals: Holly, Stephen P., Gera, Nidhi, Wang, Putianqi, Wilson, Alexander, Guan, Ziqiang, Lin, Ling, Cooley, Brian, Alfar, Hammodah R., Patil, Ruchi G., Piatt, Raymond, Leisner, Tina M., Bergmeier, Wolfgang, Majumder, Rinku, Parise, Leslie V.
Format: Artigo
Idioma:Inglês
Publicat: American Society of Hematology 2019
Matèries:
Platelets and Thrombopoiesis
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6880913/
https://ncbi.nlm.nih.gov/pubmed/31770438
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2018030767
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars