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Chemoproteomic Discovery of AADACL1 as a Novel Regulator of Human Platelet Activation

A comprehensive knowledge of the platelet proteome is necessary for understanding thrombosis and for conceiving novel antiplatelet therapies. To discover new biochemical pathways in human platelets, we screened platelets with a carbamate library designed to interrogate the serine hydrolase subproteo...

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Detalhes bibliográficos
Main Authors: Holly, Stephen P., Chang, Jae Won, Li, Weiwei, Niessen, Sherry, Phillips, Ryan M., Piatt, Raymond, Black, Justin L., Smith, Matthew C., Boulaftali, Yacine, Weyrich, Andrew S., Bergmeier, Wolfgang, Cravatt, Benjamin F., Parise, Leslie V.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3948353/
https://ncbi.nlm.nih.gov/pubmed/23993462
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chembiol.2013.07.011
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