Sptlc1 is essential for myeloid differentiation and hematopoietic homeostasis

Serine palmitoyltransferase (SPT) long-chain base subunit 1 (SPTLC1) is 1 of the 2 main catalytic subunits of the SPT complex, which catalyzes the first and rate-limiting step of sphingolipid biosynthesis. Here, we show that Sptlc1 deletion in adult bone marrow (BM) cells results in defective myeloi...

Descripció completa

Guardat en:
Dades bibliogràfiques
Publicat a:Blood Adv
Autors principals: Parthibane, Velayoudame, Acharya, Diwash, Srideshikan, Sargur Madabushi, Lin, Jing, Myerscough, Dru G., Abimannan, Thiruvaimozhi, Vijaykrishna, Nagampalli, Blankenberg, Daniel, Bondada, Lavanya, Klarmann, Kimberly D., Fox, Stephen D., Andresson, Thorkell, Tessarollo, Lino, Acharya, Usha, Keller, Jonathan R., Acharya, Jairaj K.
Format: Artigo
Idioma:Inglês
Publicat: American Society of Hematology 2019
Matèries:
Hematopoiesis and Stem Cells
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6880889/
https://ncbi.nlm.nih.gov/pubmed/31751474
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2019000729
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars