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Chemical tuning of photoswitchable azobenzenes: a photopharmacological case study using nicotinic transmission

We have developed photochromic probes for the nicotinic acetylcholine receptor that exploit the unique chemical properties of the tetrafluoroazobenzene (4FAB) scaffold. Ultraviolet light switching and rapid thermal relaxation of the metastable cis configuration are the main drawbacks associated with...

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Bibliografske podrobnosti
izdano v:Beilstein J Org Chem
Main Authors: Sansalone, Lorenzo, Zhao, Jun, Richers, Matthew T, Ellis-Davies, Graham C R
Format: Artigo
Jezik:Inglês
Izdano: Beilstein-Institut 2019
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6880823/
https://ncbi.nlm.nih.gov/pubmed/31807216
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3762/bjoc.15.274
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