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Chemical tuning of photoswitchable azobenzenes: a photopharmacological case study using nicotinic transmission

We have developed photochromic probes for the nicotinic acetylcholine receptor that exploit the unique chemical properties of the tetrafluoroazobenzene (4FAB) scaffold. Ultraviolet light switching and rapid thermal relaxation of the metastable cis configuration are the main drawbacks associated with...

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Detalles Bibliográficos
Publicado en:Beilstein J Org Chem
Autores principales: Sansalone, Lorenzo, Zhao, Jun, Richers, Matthew T, Ellis-Davies, Graham C R
Formato: Artigo
Lenguaje:Inglês
Publicado: Beilstein-Institut 2019
Materias:
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6880823/
https://ncbi.nlm.nih.gov/pubmed/31807216
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3762/bjoc.15.274
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