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Chemical tuning of photoswitchable azobenzenes: a photopharmacological case study using nicotinic transmission

We have developed photochromic probes for the nicotinic acetylcholine receptor that exploit the unique chemical properties of the tetrafluoroazobenzene (4FAB) scaffold. Ultraviolet light switching and rapid thermal relaxation of the metastable cis configuration are the main drawbacks associated with...

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Detalhes bibliográficos
Publicado no:Beilstein J Org Chem
Main Authors: Sansalone, Lorenzo, Zhao, Jun, Richers, Matthew T, Ellis-Davies, Graham C R
Formato: Artigo
Idioma:Inglês
Publicado em: Beilstein-Institut 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6880823/
https://ncbi.nlm.nih.gov/pubmed/31807216
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3762/bjoc.15.274
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