Obesity-Associated Extracellular Matrix Remodeling Promotes a Macrophage Phenotype Similar to Tumor-Associated Macrophages

Obesity is associated with adipose inflammation, defined by macrophages encircling dead adipocytes, as well as extracellular matrix (ECM) remodeling and increased risk of breast cancer. Whether ECM affects macrophage phenotype in obesity is uncertain. A better understanding of this relationship coul...

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Publicat a:Am J Pathol
Autors principals: Springer, Nora L., Iyengar, Neil M., Bareja, Rohan, Verma, Akanksha, Jochelson, Maxine S., Giri, Dilip D., Zhou, Xi K., Elemento, Olivier, Dannenberg, Andrew J., Fischbach, Claudia
Format: Artigo
Idioma:Inglês
Publicat: American Society for Investigative Pathology 2019
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6880774/
https://ncbi.nlm.nih.gov/pubmed/31323189
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2019.06.005
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