Obesity-Associated Extracellular Matrix Remodeling Promotes a Macrophage Phenotype Similar to Tumor-Associated Macrophages

Obesity is associated with adipose inflammation, defined by macrophages encircling dead adipocytes, as well as extracellular matrix (ECM) remodeling and increased risk of breast cancer. Whether ECM affects macrophage phenotype in obesity is uncertain. A better understanding of this relationship coul...

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Detalhes bibliográficos
Publicado no:Am J Pathol
Main Authors: Springer, Nora L., Iyengar, Neil M., Bareja, Rohan, Verma, Akanksha, Jochelson, Maxine S., Giri, Dilip D., Zhou, Xi K., Elemento, Olivier, Dannenberg, Andrew J., Fischbach, Claudia
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6880774/
https://ncbi.nlm.nih.gov/pubmed/31323189
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2019.06.005
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