Twenty Novel Disease Group-Specific and 12 New Shared Macrophage Pathways in Eight Groups of 34 Diseases Including 24 Inflammatory Organ Diseases and 10 Types of Tumors

The mechanisms underlying pathophysiological regulation of tissue macrophage (Mφ) subsets remain poorly understood. From the expression of 207 Mφ genes comprising 31 markers for 10 subsets, 45 transcription factors (TFs), 56 immunometabolism enzymes, 23 trained immunity (innate immune memory) enzyme...

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Publicado en:Front Immunol
Autores principales: Lai, Bin, Wang, Jiwei, Fagenson, Alexander, Sun, Yu, Saredy, Jason, Lu, Yifan, Nanayakkara, Gayani, Yang, William Y., Yu, Daohai, Shao, Ying, Drummer, Charles, Johnson, Candice, Saaoud, Fatma, Zhang, Ruijing, Yang, Qian, Xu, Keman, Mastascusa, Kevin, Cueto, Ramon, Fu, Hangfei, Wu, Susu, Sun, Lizhe, Zhu, Peiqian, Qin, Xuebin, Yu, Jun, Fan, Daping, Shen, Ying H., Sun, Jianxin, Rogers, Thomas, Choi, Eric T., Wang, Hong, Yang, Xiaofeng
Formato: Artigo
Lenguaje:Inglês
Publicado: Frontiers Media S.A. 2019
Materias:
Immunology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6880770/
https://ncbi.nlm.nih.gov/pubmed/31824480
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.02612
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