Flow-enhanced priming of hESCs through H2B acetylation and chromatin decondensation

BACKGROUND: Distinct mechanical stimuli are known to manipulate the behaviors of embryonic stem cells (ESCs). Fundamental rationale of how ESCs respond to mechanical forces and the potential biological effects remain elusive. Here we conducted the mechanobiological study for hESCs upon mechanomics a...

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Enregistré dans:
Détails bibliographiques
Publié dans:Stem Cell Res Ther
Auteurs principaux: Wang, Jiawen, Wu, Yi, Zhang, Xiao, Zhang, Fan, Lü, Dongyuan, Shangguan, Bing, Gao, Yuxin, Long, Mian
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2019
Sujets:
Research
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6880446/
https://ncbi.nlm.nih.gov/pubmed/31775893
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13287-019-1454-z
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