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Flow-enhanced priming of hESCs through H2B acetylation and chromatin decondensation

BACKGROUND: Distinct mechanical stimuli are known to manipulate the behaviors of embryonic stem cells (ESCs). Fundamental rationale of how ESCs respond to mechanical forces and the potential biological effects remain elusive. Here we conducted the mechanobiological study for hESCs upon mechanomics a...

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Publicado en:Stem Cell Res Ther
Autores principales: Wang, Jiawen, Wu, Yi, Zhang, Xiao, Zhang, Fan, Lü, Dongyuan, Shangguan, Bing, Gao, Yuxin, Long, Mian
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2019
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6880446/
https://ncbi.nlm.nih.gov/pubmed/31775893
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13287-019-1454-z
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