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Acute inhibition of protein deacetylases does not impact skeletal muscle insulin action

Whether the histone deacetylase (HDAC) and sirtuin families of protein deacetylases regulate insulin-stimulated glucose uptake, independent of their transcriptional effects, has not been studied. Our objective was to determine the nontranscriptional role of HDACs and sirtuins in regulation of skelet...

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Bibliografiske detaljer
Udgivet i:Am J Physiol Cell Physiol
Main Authors: Martins, Vitor F., Begur, Maedha, Lakkaraju, Shivani, Svensson, Kristoffer, Park, Ji, Hetrick, Byron, McCurdy, Carrie. E., Schenk, Simon
Format: Artigo
Sprog:Inglês
Udgivet: American Physiological Society 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6879879/
https://ncbi.nlm.nih.gov/pubmed/31461343
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00159.2019
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