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Lrrc55 is a novel prosurvival factor in pancreatic islets
Pancreatic islets adapt to the increase in insulin demand during pregnancy by upregulating β-cell number, insulin synthesis, and secretion. These changes require prolactin receptor (PrlR) signaling, as mice with PrlR deletion are glucose intolerant with a lower β-cell mass. Prolactin also prevents β...
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| Publicado no: | Am J Physiol Endocrinol Metab |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Physiological Society
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6879869/ https://ncbi.nlm.nih.gov/pubmed/31526288 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.00028.2019 |
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