Cationic Amino Acid Transporter-1-Mediated Arginine Uptake Is Essential for Chronic Lymphocytic Leukemia Cell Proliferation and Viability

Interfering with tumor metabolism by specifically restricting the availability of extracellular nutrients is a rapidly emerging field of cancer research. A variety of tumor entities depend on the uptake of the amino acid arginine since they have lost the ability to synthesize it endogenously, that i...

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Detalles Bibliográficos
Publicado en:Front Oncol
Main Authors: Werner, Anke, Pieh, Daniel, Echchannaoui, Hakim, Rupp, Johanna, Rajalingam, Krishnaraj, Theobald, Matthias, Closs, Ellen I., Munder, Markus
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2019
Assuntos:
Oncology
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6879669/
https://ncbi.nlm.nih.gov/pubmed/31824848
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2019.01268
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