The dimeric ectodomain of the alkali-sensing insulin receptor–related receptor (ectoIRR) has a droplike shape

Insulin receptor–related receptor (IRR) is a receptor tyrosine kinase of the insulin receptor family and functions as an extracellular alkali sensor that controls metabolic alkalosis in the regulation of the acid–base balance. In the present work, we sought to analyze structural features of IRR by c...

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Bibliografische gegevens
Gepubliceerd in:J Biol Chem
Hoofdauteurs: Shtykova, Eleonora V., Petoukhov, Maxim V., Mozhaev, Andrey A., Deyev, Igor E., Dadinova, Liubov A., Loshkarev, Nikita A., Goryashchenko, Alexander S., Bocharov, Eduard V., Jeffries, Cy M., Svergun, Dmitri I., Batishchev, Oleg V., Petrenko, Alexander G.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Biochemistry and Molecular Biology 2019
Onderwerpen:
Protein Structure and Folding
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6879334/
https://ncbi.nlm.nih.gov/pubmed/31615897
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.010390
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