Early Bayesian Dose Adjustment of Vancomycin Continuous Infusion in Children in a Randomized Controlled Trial

Methicillin-resistant staphylococcal infections are a global burden. Area under the concentration-time curve to MIC (AUC/MIC) ratio is the pharmacokinetic (PK) parameter that best predicts vancomycin efficacy. Its therapeutic range is narrow, difficult to achieve because of a wide intersubject varia...

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Publicado en:Antimicrob Agents Chemother
Autores principales: Berthaud, Romain, Benaboud, Sihem, Hirt, Déborah, Genuini, Mathieu, Oualha, Mehdi, Castelle, Martin, Briand, Coralie, Artru, Solène, Norsa, Lorenzo, Boyer, Olivia, Foissac, Frantz, Bouazza, Naïm, Tréluyer, Jean-Marc
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2019
Materias:
Pharmacology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6879247/
https://ncbi.nlm.nih.gov/pubmed/31591117
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01102-19
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