Differential phosphorylation determines the repressor and activator potencies of GLI1 proteins and their efficiency in modulating the HPV life cycle

The Sonic Hedgehog (Shh) signalling pathway plays multiple roles during embryonic development and under pathological conditions. Although the core components of the Shh pathway are conserved, the regulation of signal transduction varies significantly among species and cell types. Protein kinases Ulk...

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Publicado en:PLoS One
Autores principales: Piirsoo, Alla, Pink, Anne, Kasak, Lagle, Kala, Martin, Kasvandik, Sergo, Ustav, Mart, Piirsoo, Marko
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2019
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6879148/
https://ncbi.nlm.nih.gov/pubmed/31770404
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0225775
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