Differential phosphorylation determines the repressor and activator potencies of GLI1 proteins and their efficiency in modulating the HPV life cycle

The Sonic Hedgehog (Shh) signalling pathway plays multiple roles during embryonic development and under pathological conditions. Although the core components of the Shh pathway are conserved, the regulation of signal transduction varies significantly among species and cell types. Protein kinases Ulk...

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Udgivet i:PLoS One
Main Authors: Piirsoo, Alla, Pink, Anne, Kasak, Lagle, Kala, Martin, Kasvandik, Sergo, Ustav, Mart, Piirsoo, Marko
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2019
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6879148/
https://ncbi.nlm.nih.gov/pubmed/31770404
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0225775
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