Protein kinase inhibitor SU6668 attenuates positive regulation of Gli proteins in cancer and multipotent progenitor cells

Observations that Glioma-associated transcription factors Gli1 and Gli2 (Gli1/2), executers of the Sonic Hedgehog (Shh) signaling pathway and targets of the Transforming Growth Factor β (TGF-β) signaling axis, are involved in numerous developmental and pathological processes unveil them as attractiv...

Full description

Saved in:
Bibliographic Details
Main Authors: Piirsoo, Alla, Kasak, Lagle, Kauts, Mari-Liis, Loog, Mart, Tints, Kairit, Uusen, Piia, Neuman, Toomas, Piirsoo, Marko
Format: Artigo
Language:Inglês
Published: Elsevier Pub. Co 2014
Subjects:
Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3946003/
https://ncbi.nlm.nih.gov/pubmed/24418624
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbamcr.2014.01.003
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items