Protein kinase inhibitor SU6668 attenuates positive regulation of Gli proteins in cancer and multipotent progenitor cells

Observations that Glioma-associated transcription factors Gli1 and Gli2 (Gli1/2), executers of the Sonic Hedgehog (Shh) signaling pathway and targets of the Transforming Growth Factor β (TGF-β) signaling axis, are involved in numerous developmental and pathological processes unveil them as attractiv...

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Detalhes bibliográficos
Main Authors: Piirsoo, Alla, Kasak, Lagle, Kauts, Mari-Liis, Loog, Mart, Tints, Kairit, Uusen, Piia, Neuman, Toomas, Piirsoo, Marko
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier Pub. Co 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3946003/
https://ncbi.nlm.nih.gov/pubmed/24418624
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbamcr.2014.01.003
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