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DAZL Regulates Germ Cell Survival through a Network of PolyA-Proximal mRNA Interactions
The RNA binding protein DAZL is essential for gametogenesis, but its direct in vivo functions, RNA targets, and the molecular basis for germ cell loss in Dazl-null mice are unknown. Here, we mapped transcriptome-wide DAZL-RNA interactions in vivo, revealing DAZL binding to thousands of mRNAs via pol...
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| Publicado no: | Cell Rep |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6878787/ https://ncbi.nlm.nih.gov/pubmed/30380414 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2018.10.012 |
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