DAZL Regulates Germ Cell Survival through a Network of PolyA-Proximal mRNA Interactions

The RNA binding protein DAZL is essential for gametogenesis, but its direct in vivo functions, RNA targets, and the molecular basis for germ cell loss in Dazl-null mice are unknown. Here, we mapped transcriptome-wide DAZL-RNA interactions in vivo, revealing DAZL binding to thousands of mRNAs via pol...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:Cell Rep
Main Authors: Zagore, Leah L., Sweet, Thomas J., Hannigan, Molly M., Weyn-Vanhentenryck, Sebastien M., Jobava, Raul, Hatzoglou, Maria, Zhang, Chaolin, Licatalosi, Donny D.
Format: Artigo
Sprog:Inglês
Udgivet: 2018
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6878787/
https://ncbi.nlm.nih.gov/pubmed/30380414
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2018.10.012
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker