ABHD2 Inhibitor Identified by Activity-Based Protein Profiling Reduces Acrosome Reaction

[Image: see text] ABHD2 is a serine hydrolase that belongs to the subgroup of the α,β-hydrolase fold-containing proteins, which is involved in virus propagation, immune response, and fertilization. Chemical tools to selectively modulate the activity of ABHD2 in an acute setting are highly desired to...

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Detalhes bibliográficos
Publicado no:ACS Chem Biol
Main Authors: Baggelaar, Marc P., den Dulk, Hans, Florea, Bogdan I., Fazio, Domenico, Bernabò, Nicola, Raspa, Marcello, Janssen, Antonius P. A., Scavizzi, Ferdinando, Barboni, Barbara, Overkleeft, Hermen S., Maccarrone, Mauro, van der Stelt, Mario
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2019
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6878212/
https://ncbi.nlm.nih.gov/pubmed/31525885
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschembio.9b00640
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