Missing self triggers NK cell-mediated chronic vascular rejection of solid organ transplants

Current doctrine is that microvascular inflammation (MVI) triggered by a transplant -recipient antibody response against alloantigens (antibody-mediated rejection) is the main cause of graft failure. Here, we show that histological lesions are not mediated by antibodies in approximately half the par...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Koenig, Alice, Chen, Chien-Chia, Marçais, Antoine, Barba, Thomas, Mathias, Virginie, Sicard, Antoine, Rabeyrin, Maud, Racapé, Maud, Duong-Van-Huyen, Jean-Paul, Bruneval, Patrick, Loupy, Alexandre, Dussurgey, Sébastien, Ducreux, Stéphanie, Meas-Yedid, Vannary, Olivo-Marin, Jean-Christophe, Paidassi, Héléna, Guillemain, Romain, Taupin, Jean-Luc, Callemeyn, Jasper, Morelon, Emmanuel, Nicoletti, Antonino, Charreau, Béatrice, Dubois, Valérie, Naesens, Maarten, Walzer, Thierry, Defrance, Thierry, Thaunat, Olivier
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6877588/
https://ncbi.nlm.nih.gov/pubmed/31767837
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-13113-5
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