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Myeloid loss of Beclin 1 promotes PD-L1(hi) precursor B cell lymphoma development
Beclin 1 (Becn1) is a key molecule in the autophagy pathway and has been implicated in cancer development. Due to the embryonic lethality of homozygous Becn1-deficient mice, the precise mechanisms and cell type–specific roles of Becn1 in regulating inflammation and cancer immunity remain elusive. He...
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| Publicado no: | J Clin Invest |
|---|---|
| Main Authors: | , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Clinical Investigation
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6877338/ https://ncbi.nlm.nih.gov/pubmed/31503548 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI127721 |
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