Caspase-8 modulates physiological and pathological angiogenesis during retina development

During developmental angiogenesis, blood vessels grow and remodel to ultimately build a hierarchical vascular network. Whether, how, cell death signaling molecules contribute to blood vessel formation is still not well understood. Caspase-8 (Casp-8), a key protease in the extrinsic cell death–signal...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: Tisch, Nathalie, Freire-Valls, Aida, Yerbes, Rosario, Paredes, Isidora, La Porta, Silvia, Wang, Xiaohong, Martín-Pérez, Rosa, Castro, Laura, Wong, Wendy Wei-Lynn, Coultas, Leigh, Strilic, Boris, Gröne, Hermann-Josef, Hielscher, Thomas, Mogler, Carolin, Adams, Ralf H., Heiduschka, Peter, Claesson-Welsh, Lena, Mazzone, Massimiliano, López-Rivas, Abelardo, Schmidt, Thomas, Augustin, Hellmut G., Ruiz de Almodovar, Carmen
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6877326/
https://ncbi.nlm.nih.gov/pubmed/31454332
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI122767
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