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FOXM1 drives proximal tubule proliferation during repair from acute ischemic kidney injury

The proximal tubule has a remarkable capacity for repair after acute injury, but the cellular lineage and molecular mechanisms underlying this repair response are incompletely understood. Here, we developed a Kim1-GFPCreER(t2) knockin mouse line (Kim1-GCE) in order to perform genetic lineage tracing...

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Библиографические подробности
Опубликовано в: :J Clin Invest
Главные авторы: Chang-Panesso, Monica, Kadyrov, Farid F., Lalli, Matthew, Wu, Haojia, Ikeda, Shiyo, Kefaloyianni, Eirini, Abdelmageed, Mai M., Herrlich, Andreas, Kobayashi, Akio, Humphreys, Benjamin D.
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Clinical Investigation 2019
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6877314/
https://ncbi.nlm.nih.gov/pubmed/31710314
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI125519
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