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Pancreatic cancer-associated inflammation drives dynamic regulation of p35 and Ebi3.
B cells are important modulators of immune responses both in autoimmunity and cancer. We have previously shown that B regulatory (Breg) cells promote pancreatic cancer via production of IL35, a heterodimeric cytokine comprised of the subunits p35 (Il12a) and Ebi3. However, it is not known how produc...
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| Veröffentlicht in: | Cytokine |
|---|---|
| Hauptverfasser: | , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2019
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6876557/ https://ncbi.nlm.nih.gov/pubmed/31472403 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cyto.2019.154817 |
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