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IL35 hinders endogenous antitumor T-cell immunity and responsiveness to immunotherapy in pancreatic cancer

Although successes in cancer immunotherapy have generated considerable excitement, this form of treatment has been largely ineffective in patients with pancreatic ductal adenocarcinoma (PDA). Mechanisms that contribute to the poor antitumor immune response in PDA are not well understood. Here, we de...

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Podrobná bibliografie
Vydáno v:Cancer Immunol Res
Hlavní autoři: Mirlekar, Bhalchandra, Michaud, Daniel, Searcy, Ryan, Greene, Kevin, Pylayeva-Gupta, Yuliya
Médium: Artigo
Jazyk:Inglês
Vydáno: 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6125203/
https://ncbi.nlm.nih.gov/pubmed/29980536
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2326-6066.CIR-17-0710
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