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IL35 hinders endogenous antitumor T-cell immunity and responsiveness to immunotherapy in pancreatic cancer

Although successes in cancer immunotherapy have generated considerable excitement, this form of treatment has been largely ineffective in patients with pancreatic ductal adenocarcinoma (PDA). Mechanisms that contribute to the poor antitumor immune response in PDA are not well understood. Here, we de...

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Библиографические подробности
Опубликовано в: :Cancer Immunol Res
Главные авторы: Mirlekar, Bhalchandra, Michaud, Daniel, Searcy, Ryan, Greene, Kevin, Pylayeva-Gupta, Yuliya
Формат: Artigo
Язык:Inglês
Опубликовано: 2018
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6125203/
https://ncbi.nlm.nih.gov/pubmed/29980536
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2326-6066.CIR-17-0710
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