A novel mouse model of sporadic colon cancer induced by combination of conditional Apc genes and chemical carcinogen in the absence of Cre recombinase

Although valuable insights into colon cancer biology have been garnered from human colon cancer cell lines and primary colonic tissues, and animal studies using human colon cancer xenografts, immunocompetent mouse models of spontaneous or chemically induced colon cancer better phenocopy human diseas...

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Detaylı Bibliyografya
Yayımlandı:Carcinogenesis
Asıl Yazarlar: Souris, Jeffrey S, Zhang, Hannah J, Dougherty, Urszula, Chen, Nai-Tzu, Waller, Joseph V, Lo, Leu-Wei, Hart, John, Chen, Chin-Tu, Bissonnette, Marc
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Oxford University Press 2019
Konular:
Carcinogenesis
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6875902/
https://ncbi.nlm.nih.gov/pubmed/30859181
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgz050
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