Maternal alloimmune IgG causes anti-glomerular basement membrane disease in perinatal transgenic mice that express human laminin α5.

Mammalian immune systems are not mature until well after birth. However, transfer of maternal IgG to the fetus and newborn usually provides immunoprotection from infectious diseases. IgG transfer occurs before birth in humans across the placenta and continues after birth across the intestine in many...

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Detalhes bibliográficos
Publicado no:Kidney Int
Main Authors: Abrahamson, Dale R., Steenhard, Brooke M., Stroganova, Larysa, Zelenchuk, Adrian, St. John, Patricia L., Petroff, Margaret G., Patarroyo, Manuel, Borza, Dorin Bogdan
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6875631/
https://ncbi.nlm.nih.gov/pubmed/31530475
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.kint.2019.06.014
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