Methane Alleviates Acetaminophen-Induced Liver Injury by Inhibiting Inflammation, Oxidative Stress, Endoplasmic Reticulum Stress, and Apoptosis through the Nrf2/HO-1/NQO1 Signaling Pathway

Acetaminophen- (APAP-) induced hepatic injury is an important clinical challenge. Oxidative stress, inflammation, apoptosis, and endoplasmic reticulum stress (ERS) contribute to the pathogenesis. Methane has potential anti-inflammatory, antioxidant, and antiapoptotic properties. This project was aim...

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Detalhes bibliográficos
Publicado no:Oxid Med Cell Longev
Main Authors: Feng, Yang, Cui, Ruixia, Li, Zeyu, Zhang, Xia, Jia, Yifan, Zhang, Xing, Shi, Jinghong, Qu, Kai, Liu, Chang, Zhang, Jingyao
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6875424/
https://ncbi.nlm.nih.gov/pubmed/31781345
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2019/7067619
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