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Penehyclidine Hydrochloride Pretreatment Ameliorates Rhabdomyolysis-Induced AKI by Activating the Nrf2/HO-1 Pathway and Allevi-ating Endoplasmic Reticulum Stress in Rats

Acute kidney injury (AKI) is one of the most severe complications of rhabdomyolysis (RM). The underlying mechanisms and potential preventions need to be investigated. Penehyclidine hydrochloride (PHC) was reported to ameliorate renal ischemia-reperfusion injury, but the effect of PHC on RM-reduced A...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Zhao, Wei, Huang, XuDong, Zhang, LiXia, Yang, XinJun, Wang, LiHui, Chen, YunShuang, Wang, JingHua, Wu, GuangLi
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4795801/
https://ncbi.nlm.nih.gov/pubmed/26987113
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0151158
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